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Mother of two, 51, dies of blood clot ‘likely’ from AstraZeneca Covid strike


Michelle Barlow, 51, began experiencing headaches and nausea about a week after receiving her first dose of the vaccine in March.

A “healthy and fit” mother of two has died from a blood clot “likely” caused by the AstraZeneca Covid-19 vaccine, an investigation says.

Michelle Barlow, 51, began experiencing headaches and nausea about a week after receiving her first dose of the vaccine in March.

She was eventually hospitalized and tragically died later that month.

Chief coroner Timothy Brenand heard that Ms Barlow, who worked as a government employee at the Department of Work and Pensions for 34 years, had suffered from blood clots likely from the vaccine.

An investigation in Bolton Coroners Court heard that the case was an “extremely rare” side effect of the AstraZeneca vaccine.

Michelle, a mother of two from Oriel in Wigan, received her first dose of the vaccine on March 7.

Ian, Michelle’s husband, told the session that in the days that followed, she began experiencing “flu-like symptoms” and later developed headaches, diarrhea and nausea.

By March 19, Ms Barlow’s symptoms had become “overwhelming” so she sought help at the Wigan Infirmary.

Doctors did tests that showed that she had a very low platelet count. She was discharged from the hospital and was asked to return for a medical examination the following week.

However, Ms Barlow’s condition failed to improve and she was admitted to hospital the next day.

Doctors suspected she had a gastroenteritis infection, the investigation heard.

Mr Barlow said the family was not able to be with her at the hospital due to Covid restrictions, and on March 22nd, he received a phone call from a nurse asking him to get to the hospital as soon as possible.

“I knew something wasn’t right,” he said. “When I got that phone call, I was expecting to go see my wife and she’ll live.”

She was eventually hospitalized at Wigan Infirmary (pictured), where she later died

She was eventually hospitalized at Wigan Infirmary (pictured), where she later died

When he arrived, Mr Barlow said his wife told him the doctors “couldn’t do anything for her”.

“The doctors came and explained,” Mr. Barlow said. “I just told them ‘You have to save her.'”

Mrs. Barlow died with her family at her bedside the next day.

Pathologist Dr Naveen Sharma described her cause of death as “multi-organ failure due to pulmonary embolism”.

He said it was possible that there was a “causal link” between the blood clot in Ms Barlow’s lungs and the AstraZeneca vaccine.

Dr. Sharma said the Medicines and Healthcare products Regulatory Agency (MHRA) this month released guidance indicating a possible link between the AstraZeneca vaccine and the “very rare” side effect of blood clots.

He said 425 cases of major blood clots had been identified in people who had taken the AstraZeneca vaccine, and he said this represented a “rare but very clearly known potential complication”.

Of the 425 cases, 215 in women and 206 in men, 154 related to blood clots in the head and 271 in other parts of the body.

Furthermore, ages ranged from 18 to 93, with 101 cases in the 50 to 59 age group, 19 of which were among the 73 fatal cases in total.

He said 24.8 million people have currently received the first dose of the AstraZeneca vaccine and 24.1 million people have been injected with the same drug.

Praising his wife, Barlow said: “She was a wonderful wife, mother and grandmother.

It was perfect. Michelle was and remains to me the most loving, caring, patient and selfless person anyone could ever meet.

It was fit and healthy. There was nothing wrong with her.

Michelle, a mother of two from Oriel in Wigan, received her first dose of the vaccine on March 7 and died within days

Michelle, a mother of two from Oriel in Wigan, received her first dose of the vaccine on March 7 and died within days

Dr Peter Kreibel, GP at Mesnes View Surgery in Wigan, said Ms Barlow had posed to get her first dose of the vaccine early due to an error in her records, which stated she was looking after her husband.

Mr Barlow told the investigation that when his wife called the practice to tell them it was a mistake, she was told: “Just get the vaccine.”

Had Ms Barlow not been in this category, Dr Kreibel said, she would not have been called upon to get the vaccine at that point.

However, he said he would have recommended her to get the vaccine because her risk of developing a blood clot was 100 times greater without the vaccine than it was with her.

It wasn’t until a CT scan of Ms Barlow’s lungs revealed a blood clot that doctors began to suspect a possible reaction to the vaccine, not gastroenteritis, Dr. Mian Ahmed, consultant physician at Wigan Hospital, told Hearing.

He said the condition – thrombocytopenia and vaccine-induced immunocoagulation (VITT) – had not been recognized at the time of her death.

Dr. Ahmed said that if the same situation arose now, he would prescribe hemoglobin, blood thinners and a CT scan to the patient sooner.

He agreed that this might have given her a “better chance” but that it was a “tough call”.

Marius Parawan, a surgeon at the hospital, said that after a CT scan, he concluded Ms Barlow’s condition was “not viable”.

In addition to her husband, Mrs. Barlow’s two sons, Matthew and Mark, were also present at the hearing along with other relatives.

Chief coroner Timothy Brenand said he would present his findings in the investigation Friday morning.

What are the risks of developing a blood clot after the AstraZeneca vaccination?

Earlier this year, British health chiefs recommended that an alternative to the AstraZeneca vaccine be offered to all under 40 due to blood clot concerns.

According to the Medicines and Healthcare products Regulatory Agency, as of September 1, there have been 416 cases of VITT and 72 deaths.

But statisticians analyzed the numbers and found that rates were slightly higher among younger adults, and females appeared to be more at risk, too.

Cambridge academics have estimated that about 1.9 out of every 100,000 people in their twenties, given the AstraZeneca vaccination, will have dangerous blood clots along with abnormally low levels of platelets (thrombocytopenia) – the specific disorder associated with stab. At 30, the number was 1.5.

They compared that to the average number of intensive care admissions for Covid that could be prevented by giving that group an injection. Then they analyzed the risk/benefit ratio in different scenarios, based on how prevalent the disease was at the time.

For example, only 0.2 ICU admissions per 100,000 people in their twenties would be prevented given the dose at the prevalence levels seen in April (below 30,000 infections per week). For adults in their 30s, the number was about 0.8.

However, it has shown that the benefits of giving the AstraZeneca vaccine to those aged 40 to 49 years outweigh the potential risks (1.7 ICU admissions per 100,000 people compared to 1.2 blood clots prevented).

But the decision to recommend those under 40 has been shown to Pfizer or Moderna instead, primarily taken only because the outbreak has been squashed to very low levels, plus the fact that young people are known to face slim odds of becoming seriously ill from Corona Virus.

Regulators insist the vaccination benefits the elderly, for whom the disease poses a much greater threat. Leading scholars believe that Jabs have already saved about 13,000 lives in England.

However, because there were so few blood clots, it made it impossible for the 10th Vaccine Advisory Committee to establish an exact age. Instead, they were only able to parse numbers by decade.

The first clots that worried people were those that appear in the veins near the brains of younger adults in a condition called CSVT (cerebral sinus venous thrombosis).

Since then, people have developed clots in other parts of their bodies and are usually associated with low numbers of platelets, which is unusual because platelets are commonly used by the immune system to build clots.

In most cases, people recover fully and blockages are generally easy to treat if caught early, but they can lead to strokes or heart or lung problems if not noticed.

Symptoms depend entirely on the location of the blood clot, as the blockage in the brain causes severe headaches. Clots in the main arteries of the abdomen can cause persistent stomach pain, and clots in the leg can cause swelling in the extremities.

Researchers in Germany believe the problem lies with the vector of adenovirus – a common cold virus used so that vaccines can enter the body.

Academics investigating this problem say complications are “completely absent” in mRNA vaccines such as Pfizer and Moderna because they have a different delivery mechanism.

Experts at Goethe University in Frankfurt and the University of Ulm, in Helmholtz say that the AstraZeneca vaccine enters the cell nucleus – a block of DNA in the middle. For comparison, Pfizer’s vaccine enters the liquid around it which acts as a protein factory.

Scientists claim that bits of coronavirus proteins that get inside the nucleus can break apart and then the unusual pieces are expelled into the bloodstream, where they can clot a small number of people.



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